Nicholas Gilpin, Ph.D.
Ph.D. Purdue University
M.S. Purdue University
B.A. University of Texas
My lab seeks to identify the underlying neurobiological mechanisms of alcohol dependence and stress disorders. We work to understand the neuropharmacology of drug reinforcement in the drug-dependent organism, and we are also interested in examining the neurobiological mechanisms of co-dependence on more than one drug. To answer these questions, we use techniques that include operant drug self-administration, acoustic startle reflex, tests of pain and mechanosensitivity, tests of anxiety-like behavior and locomotor activity, alcohol and nicotine vapor inhalation for induction of physical dependence, behavioral pharmacology, immunohistochemistry, and Western blots.
I completed my undergraduate training in Psychology at University of Texas at Austin, and my Ph.D. in Psychobiology at Indiana University-Purdue University at Indianapolis. During my graduate training, I worked with genetic models of susceptibility to alcoholism.I went on to complete a post-doctoral fellowship in the labs of Drs. George Koob and Marisa Roberto at The Scripps Research Institute in La Jolla, CA, where we used behavioral pharmacology & electrophysiology techniques to explore neural and behavioral dysregulation associated with alcohol dependence.I remain very interested in questions of addiction, and I am especially interested in understanding why and how alcohol addiction is co-morbid with addiction to other drugs and other psychiatric conditions. I am also interested in questions related to subpopulations of addicts and individual differences in propensity to consume alcohol and drugs.
Outside the lab, I am an avid runner, traveler & Longhorns sports fan.